V4

jQuery(document).ready(function($) {
   
$('.Lightbox').click(function(e) {

//prevent default action (hyperlink)
e.preventDefault();

//Get clicked link href
var image_href = $(this).attr("href");
 
       
        $('body').append('<div id="light-box"></div><div id="modal-div"></div>');
               
        var img = '<div id="dvImgClose"></div><img src="' + image_href + '" />';
        $('#light-box').html(img);
        $('#light-box').center();
        $('#modal-div').show();
$('#light-box').fadeIn();
       
        $('#dvImgClose').live('click',function(){
              $('#light-box').html('');
              $('#light-box').hide('slow');
              $('#modal-div').hide();
             
        });
       
});

});

$.fn.center = function () {
    var heightRatio = ($(window).height() != 0)
            ? this.outerHeight() / $(window).height() : 1;
    var widthRatio = ($(window).width() != 0)
            ? this.outerWidth() / $(window).width() : 1;

    this.css({
        position: 'fixed',
        margin: 0,
        top: (50*(1-heightRatio)) + "%",
        left: (50*(1-widthRatio))  + "%"
    });

    return this;
}

////////////////////////////////////////////


#light-box {
   
   box-shadow:2px 2px 10px 10px #C9C9C9;
   -webkit-box-shadow:2px 2px 10px 10px #C9C9C9;
   -moz-box-shadow:2px 2px 10px 10px #C9C9C9;
 
   display:none;z-index:99999;position:absolute;border:solid 5px #ffffff
    }
   
 #light-box img{
     max-width:500px;max-height:500px
 }
   
   
#modal-div{
 z-index:9999;
 display:none;
 position:fixed;
 top:0;
 left:0;
 width:100%;
 height:100%;
 background-color:#000;
 -moz-opacity:0.5;
 opacity:.50;
 filter:alpha(opacity=50);
}

#dvImgClose {
background: url(http://wn7x64-37c16bs.blr.amer.dell.com/en/widgetfiles/ed28fe6f19b540688dc33c6ff4195ef8/d/fancy_close.png?m=634981602706435601);
width: 30px;
height: 30px;
float: left;
position: absolute;
margin-top: -21px;
right: -22px;
cursor:pointer;
}
////////////////////////////////////////////////



<p><a class="Lightbox" href="/cfs-file.ashx/__key/communityserver-discussions-components-files/4680/5241.Chrysanthemum.jpg"><img border="0" alt=" " src="/resized-image.ashx/__size/550x250/__key/communityserver-discussions-components-files/4680/5241.Chrysanthemum.jpg" /></a></p>
<p>This is non-light</p>
<p><a href="/cfs-file.ashx/__key/communityserver-discussions-components-files/4680/1778.Penguins.jpg"><img border="0" alt=" " src="/resized-image.ashx/__size/350x350/__key/communityserver-discussions-components-files/4680/1778.Penguins.jpg" /></a></p>
<p>&nbsp;again one Light box</p>
<p><a class="Lightbox" href="/cfs-file.ashx/__key/communityserver-discussions-components-files/4680/8345.Penguins.jpg"><img src="/resized-image.ashx/__size/150x0/__key/communityserver-discussions-components-files/4680/8345.Penguins.jpg" border="0" alt=" " /></a></p>